Captopril improves impaired endothelium-dependent vasodilation in hypertensive patients.

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Captopril improves impaired endothelium-dependent vasodilation in hypertensive patients.

Animal studies suggest that some angiotensin converting enzyme inhibitors augment endothelium-dependent vasorelaxation. We aimed to determine if captopril augments endothelium-dependent vasodilation in middle-aged hypertensive patients. By using strain-gauge plethysmography, forearm vasodilation evoked with intra-arterial acetylcholine (4, 8, 16, and 24 micrograms/min) or nitroprusside (0.2, 0....

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ژورنال

عنوان ژورنال: Hypertension

سال: 1992

ISSN: 0194-911X,1524-4563

DOI: 10.1161/01.hyp.20.2.175